Chronotropic Incompetence: A Case Report
نویسندگان
چکیده
منابع مشابه
Sinus bradycardia and chronotropic incompetence associated with single-agent itraconazole antifungal therapy: A case report
Adverse cardiac effects are a known, albeit infrequent, complication of azole antifungal drug therapy. Most often, cardiotoxicity is the result of drug–drug interactions due to azole inhibition of CYP3A4, but also of CYP2C19 and CYP2C9, leading to increased serum levels of concomitantly administered medications that require hepatic metabolism. Adverse interactions of azole antifungal drugs with...
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A clear association between chronotropic incompetence and increased mortality has been established by a variety of studies in patients with coronary artery disease as well as in healthy individuals. These results gave rise to speculation that rate responsive stimulation might improve prognosis in pacemaker (PM) patients with concomitant chronotropic incompetence. To date, however, no study was ...
متن کاملChronotropic incompetence in heart failure.
The relationship between heart rate (HR) during exercise and exercise capacity in patients with heart failure due to left ventricular systolic dysfunction remains unclear. The accepted diagnostic criterion for chronotropic incompetence (CI), a maximum agepredicted heart rate (MA-PHR) 85%, is seen in 50% of patients with severe heart failure on contemporary medical therapy (1). Whether the lesse...
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For practical purpose, most studies define CI as the incapacity to reach 80% of heart rate (HR) reserve according to the formula: HR reserve = (peak HR – resting HR) / (maximum HR – resting HR) x 100. It has been suggested that the definition of CI should be assessed when the diagnostic method uses positive inotropic drugs to induce HR increase. It is necessary to better understand which practi...
متن کاملChronotropic incompetence: a proposal for definition and diagnosis.
Between 1958 and 1960 Astrand documented the normal heart rate response to exercise in healthy individuals and noted that the maximum heart rate decreased with age.' 2 A reduced cardiac chronotropic response to isoprenaline has been reported in elderly subjects and alterations in catecholamineadrenergic receptor interactions may be responsible for this change of cardiovascular regulation in the...
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ژورنال
عنوان ژورنال: Congestive Heart Failure
سال: 2001
ISSN: 1527-5299,1751-7133
DOI: 10.1111/j.1527-5299.2001.00251.x